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Disease course in a patient with TEN (SCORTEN 4) associated with cancer treatment. Disease progression was observed during high-dose intravenous methylprednisolone treatment and the patient developed persistent hyperglycaemia. JAK1i rescue therapy with abrocitinib was initiated on day 4, resulting in visible cessation of progression within 48 h and initial re-epithelialization within 4 days. Top, photographs of the back of the patient, showing the degree of re-epithelialization at the indicated timepoints after hospital admission. Bottom, Treatment schedule. Arrow marks start of abrocitinib treatment. Study: Spatial proteomics identifies JAKi as treatment for a lethal skin disease

Breakthrough Study Reveals JAK Inhibitors as Promising Treatment for Life-Threatening Skin...

Leah Sirama - 0
CheekAge: Next-gen epigenetic clock accurately predicts mortality risk

Unlocking Longevity: CheekAge’s Revolutionary Epigenetic Clock Predicts Mortality Risk with Unprecedented...

Leah Sirama - 0
Study: Core and accessory genomic traits of Vibrio cholerae O1 drive lineage transmission and disease severity. Image Credit: Kateryna Kon/Shutterstock.com

Breakthrough Study Reveals Genetic Secrets Behind Cholera Bacteria’s Deadly Prowess

Leah Sirama - 0
Study: Clinical evaluation of a machine learning–based early warning system for patient deterioration. Image Credit: LALAKA/Shutterstock.com

Transforming Patient Outcomes: How a Groundbreaking Machine Learning System is Slashing...

Leah Sirama - 0
Review: Early-onset cancers: Biological bases and clinical implications. Image Credit: Lightspring / Shutterstock

Urgent Investigation Launched: Scientists Unravel the Surge in Early-Onset Cancers and...

Leah Sirama - 0

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