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Disease course in a patient with TEN (SCORTEN 4) associated with cancer treatment. Disease progression was observed during high-dose intravenous methylprednisolone treatment and the patient developed persistent hyperglycaemia. JAK1i rescue therapy with abrocitinib was initiated on day 4, resulting in visible cessation of progression within 48 h and initial re-epithelialization within 4 days. Top, photographs of the back of the patient, showing the degree of re-epithelialization at the indicated timepoints after hospital admission. Bottom, Treatment schedule. Arrow marks start of abrocitinib treatment. Study: Spatial proteomics identifies JAKi as treatment for a lethal skin disease

Breakthrough Study Reveals JAK Inhibitors as Promising Treatment for Life-Threatening Skin...

Leah Sirama - 0
Ubiquigent partners with Alleo Labs to advance DUB-targeting therapies

Ubiquigent Teams Up with Alleo Labs to Pioneer Innovative DUB-Targeting Therapies,...

Leah Sirama - 0
Houston Methodist researchers join national consortium to develop herpesvirus vaccine

Houston Methodist Researchers Collaborate with National Consortium to Pioneer Groundbreaking Herpesvirus...

Leah Sirama - 0
New deep-learning framework identifies non-addictive pain relief options

Revolutionary Deep-Learning Framework Uncovers Non-Addictive Pain Relief Solutions: A Breakthrough in...

Leah Sirama - 0
Overcoming CRISPR's side effects for therapeutic applications

Revolutionizing Gene Editing: Researchers Tackle CRISPR’s Side Effects to Unlock New...

Leah Sirama - 0
Researchers discover potential therapeutic approach for triple negative breast cancer

Breakthrough Research Unveils Promising New Treatment for Triple Negative Breast Cancer

Leah Sirama - 0
CRISPR-Cas13 emerges as a game changer in RNA-targeted therapies

Revolutionizing Medicine: How CRISPR-Cas13 is Transforming RNA-Targeted Therapies for Disease Treatment

Leah Sirama - 0
AI-powered treatment allocation improves public health outcomes

Revolutionizing Care: How AI-Powered Treatment Allocation is Transforming Public Health Outcomes

Leah Sirama - 0
New research network focuses on high-priority viruses

New Research Network Launched to Target High-Priority Viruses: Aiming for Breakthroughs...

Leah Sirama - 0
Asimov launches AAV Edge, a suite of AI models, host cells, and genetic tools for end-to-end gene therapy development

Asimov Unveils AAV Edge: Revolutionary AI Models and Genetic Tools Set...

Leah Sirama - 0
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